“Scores of Peace Corps volunteers are coming forward saying that over the past 12 years they suffered crippling paranoia, anxiety, hallucinations, memory loss, suicidal behavior and physical ailments from seizures to vision difficulty because of the drug handed out by government doctors to prevent malaria.”

-UPI:Lariam and Peace Corps - Mark Benjamin, Dan Olmsted - 2002

“Mefloquine has been considered to be a safe drug; the commonly recognized adverse effects include dizziness, nausea, vomiting and loose stools. However, recent reports in the literature, as well as notifications to the drug manufacturer and WHO, have suggested that more severe neurological reactions may be associated with its use. These have included severe depression, psychotic episodes and seizures.”

- Adverse Effects of the Antimalarial Drug Mefloquine - World Health Organization (WHO) - 1989

“A great deal of clinical experience indicates, however, that these reports seriously underestimate the prevalence of side effects in travellers: only rarely does a week pass in which I am not informed (at the Hospital for Tropical Diseases) by at least one traveller of his or her personal experience of side effects of mefloquine (many of them severe) or of similar symptoms in a colleague or fellow traveller. Many travellers refuse to take mefloquine in the light of their experience of its neuropsychiatric side effects.” 

-Malaria prophylaxis. Mefloquine toxicity should limit its use to treatment alone - G C Cook - 1995